Complete case intake
Capture key clinical details, imaging notes, pathology context, and referral intent in one guided flow.
A secure referral pathway for physicians seeking expert multidisciplinary review of rare sarcoma and rare tumor cases.
Submit structured case referrals, support expert triage, and receive a documented advisory recommendation with relevant evidence and bibliography.
Referrals are intended for verified healthcare professionals involved in the management of rare cancer cases.
Account approval by the coordination team is required before case submission.
Eligible cases should require rare tumor expertise before a diagnostic or therapeutic decision.
| Eligible case type | Typical referral intent | Clarification |
|---|---|---|
| Confirmed or suspected sarcomas | Diagnostic orientation, pathology review, treatment sequencing. | Includes cases where subtype, grade, or optimal treatment sequence is uncertain. |
| Rare or ultra-rare solid tumors | Expert input before major therapeutic decision. | For tumors requiring specialist interpretation beyond routine local pathways. |
| Uncertain or complex diagnosis | Pathology, imaging, and clinical-context review. | Suitable when diagnostic confidence affects treatment planning. |
| Complex molecular findings | Molecular testing / genomic interpretation guidance. | Includes actionable variants, rare fusions, or unclear biomarker significance. |
| Treatment sequencing questions | Surgery, radiotherapy, systemic therapy, or trial orientation. | This portal is not intended for emergency care or direct patient self-referral. |
A secure physician portal supporting structured referral of rare sarcoma and rare tumor cases to a central expert board / virtual tumor board.
Capture key clinical details, imaging notes, pathology context, and referral intent in one guided flow.
Route cases toward appropriate expertise with clear status signals and concise review milestones.
Support collaboration between referring physicians, national centers, and specialist tumor boards.
The board issues an advisory recommendation supported by expert review and relevant bibliography.
The recommendation is advisory. The referring clinician remains responsible for final patient management decisions.
Structured national workflow from referral submission to advisory report and follow-up request. Initially, board meetings may be scheduled approximately monthly, depending on case volume and urgency.
Clinical data, diagnostic evidence, and the referral question are entered through the secure portal.
Required documentation and consent status are reviewed before triage.
A fellow prepares case orientation and relevant evidence references.
Disease-specific experts are identified based on diagnosis, molecular findings, and clinical question.
The case is discussed in a scheduled multidisciplinary board session.
A documented recommendation is issued and follow-up information is requested.
Designed for accountable clinical collaboration, institutional oversight, and secure handling of sensitive referral information.
Greek Sarcoma & Rare Cancers Group.
Referrers must confirm consent before submitting clinical data for board review.
Cases use coded Case IDs and limited identifiers to support secure clinical review.
Access is restricted by role for referrers, coordinators, fellows, experts, and administrators.
Submissions, views, board decisions, and recommendations are recorded for accountability.
Recommendations are advisory only. Final patient management remains with the treating clinician.
For institutional access, referral onboarding, or national center participation, contact the RareOnco Greece coordination team.
Standard operating procedures for rare tumor referrals.
All submitted data is handled under GDPR-aligned governance and institutional access controls.
Automated case masking uses Case IDs to support review workflows while reducing unnecessary exposure of direct identifiers.
The referring clinician and institution maintain primary clinical responsibility for patient management.
| Case | Submitted | Tumor | Urgency | Status | Owner | Next Action | Open |
|---|---|---|---|---|---|---|---|
| Local coded ID: PID-7814 | May 26, 2026 | Soft Tissue Sarcoma | High | Missing Information | Referring Clinician | Upload pathology report | |
| Local coded ID: PID-4502 | May 24, 2026 | GIST | Standard | Scheduled for Board | Expert Board | Await recommendation | |
| Local coded ID: PID-3390 | May 19, 2026 | Osteosarcoma | Low | Recommendation Issued | Board Process Complete | Review recommendation | |
| Local coded ID: PID-1187 | May 16, 2026 | Unknown Primary | High | Follow-up Overdue (12 days overdue) | Referring Clinician | Submit follow-up outcome |
Only referrals submitted by your account or institution are shown. Access is role-based and audit-tracked.
Provide the clinical context required for national specialist triage.
Review the submitted referral, current workflow status, board review outcome, evidence package, follow-up obligations, and audit trail for this case.
Should molecular confirmation be obtained before systemic treatment escalation in this sarcoma subtype?
Should molecular confirmation be obtained before systemic treatment escalation in this sarcoma subtype?
Rare Tumor Board Recommendation REC-2026-0142 issued by the Greek Sarcoma & Rare Cancers Group for case RCG-2026-0148.
Should molecular confirmation be obtained before systemic treatment escalation in this sarcoma subtype?
Complete molecular confirmation before treatment escalation, with external sarcoma pathology review and referral to a sarcoma center for integrated systemic therapy planning once subtype confirmation is available.
The board agreed that diagnostic confidence depends on molecular confirmation and external sarcoma pathology review before definitive treatment sequencing.
Complete molecular confirmation before treatment escalation, with referral to a sarcoma center for integrated systemic therapy planning once subtype confirmation is available.
Screen for molecularly matched trials or rare sarcoma registry enrollment if fusion testing confirms an actionable or ultra-rare subtype.
The board considered diagnostic uncertainty, molecular subtype impact on treatment selection, and the risk of premature escalation without confirmed sarcoma classification.
This recommendation is advisory and does not replace institutional clinical responsibility or local multidisciplinary decision-making. Final treatment decisions remain with the treating physician and institution.
No board recommendation has been issued yet.
Issued: 15 Jun 2026 | Issued by: Greek Sarcoma & Rare Cancers Group | Chair: Dr. Eleni Papadopoulou | Coordinating fellow: Dr. N. Markou | Evidence package: OncoAI Bibliography package reviewed by fellow
Should molecular confirmation be obtained before systemic treatment escalation in this sarcoma subtype?
Complete molecular confirmation before treatment escalation, with referral to a sarcoma center for integrated systemic therapy planning once subtype confirmation is available.
Screen for molecularly matched trials or rare sarcoma registry enrollment if fusion testing confirms an actionable or ultra-rare subtype.
The board considered diagnostic uncertainty, the impact of molecular subtype on treatment selection, and the risk of premature escalation without confirmed sarcoma classification. Molecular confirmation is essential for evidence-based therapeutic decision-making in this case.
This recommendation is advisory and does not replace institutional clinical responsibility or local multidisciplinary decision-making. Final treatment decisions remain with the treating physician and institutional tumor board.
Submitted referral data. This information was provided by the referring clinician and is not board-generated content.
This section reflects data submitted by the referring clinician. This is NOT board-generated content and reflects the patient and clinical status at time of submission (24 May 2026).
Additional evidence may be submitted after referral creation when requested by the coordination team or when new clinical information becomes available.
| File name | Category | Uploaded by | Upload date | Version | Status | Actions |
|---|---|---|---|---|---|---|
| Referral Form PDF | Referral Form | Uploaded by referrer | 24 May 2026 | v1 | Available | |
| Histopathology Report | Pathology | Uploaded by referrer | 24 May 2026 | v1 | Available | |
| Additional pathology report uploaded by referring clinician | Pathology | Demo Clinician | 12 Jun 2026 | v2 | Available | |
| Molecular / NGS Request | Molecular | Uploaded by referrer | 24 May 2026 | v1 | Results pending | |
| Imaging Access Link | Imaging | Uploaded by referrer | 24 May 2026 | v1 | Available | |
| Board Recommendation Report | Board Report | Generated by board | 15 Jun 2026 | v1 | Issued |
No files have been uploaded yet.
Additional clinical or laboratory evidence may be submitted after the initial referral to support recommendation implementation or document clinical changes.
The MDT reviewed the submitted referral, pathology report, staging imaging, and pending molecular testing request. The discussion focused on whether treatment escalation should wait for sarcoma subtype confirmation.
Fusion testing and external pathology orientation remain pending. Referring team should submit updated molecular results when available.
Board process completed and the case moved to formal advisory recommendation issuance on 15 Jun 2026.
The case was presented by Dr. N. Markou and reviewed in detail by all participating specialties. The board concurred that:
Diagnostic-Molecular Recommendation — This case requires diagnostic clarification through molecular testing before systemic treatment planning can be finalized. The recommendation emphasizes diagnostic pathways and molecular interpretation guidance.
Longitudinal follow-up reporting supports registry quality, outcome analysis and future rare cancer research.
If follow-up is overdue by more than 60 days, new referral submissions may be blocked.
| Timepoint | Submission Date | Submitted By | Patient Status | Disease Status | Current Therapy | Recommendation Applied | Outcome Summary |
|---|
No follow-up submissions have been recorded yet. The first expected follow-up is due on 15 Sep 2026.
Submit the follow-up outcome for RCG-2026-0148 to keep registry data complete and maintain referral workflow eligibility.
Due | Due date: 15 Sep 2026 | No previous follow-up submitted
Follow-up submission history will appear here after submission.
This bibliography package is AI-assisted and fellow-reviewed before use in the board recommendation.
Relevance to case: supports integration of molecular confirmation into treatment planning for high-grade soft tissue sarcoma.
Relevance to case: supports fusion testing and NGS panel review when histology remains diagnostically broad.
Relevance to case: contextualizes how fusion status can affect systemic therapy selection and clinical trial orientation.
Relevance to case: identifies trial orientation pathways after molecular subtype confirmation.
No OncoAI Bibliography package is attached yet.
Evidence sources reviewed by board fellow and used to support this recommendation. AI-assisted curation with manual peer review by Dr. N. Markou.
| Date | Actor | Role | Category | Action | Notes |
|---|---|---|---|---|---|
| 24 May 2026 | Demo Clinician | Referring Clinician | Referral | Referral submitted by referring clinician | Case RCG-2026-0148 created with coded local ID PID-7814. |
| 25 May 2026 | Coordination Team | Coordinator | Review | Completeness review completed by coordination team | Referral accepted for fellow triage. |
| 27 May 2026 | Dr. N. Markou | Assigned Fellow | Review | Fellow assigned | Evidence preparation and bibliography review initiated. |
| 12 Jun 2026 | Demo Clinician | Referring Clinician | Evidence Upload | Additional pathology report uploaded by referring clinician | Additional pathology context attached as v2. |
| 13 Jun 2026 | Coordination Team | Coordinator | Board | Board session scheduled | Scheduled for Sarcoma & Rare Tumors Board on 15 Jun 2026. |
| 14 Jun 2026 | Dr. N. Markou | Assigned Fellow | Review | OncoAI Bibliography package reviewed by fellow | Package OAI-RCG-2026-0148 approved for board use. |
| 15 Jun 2026 | Dr. Eleni Papadopoulou | Board Chair | Recommendation | Recommendation issued by board chair | Official board recommendation REC-2026-0142 issued. |
| 15 Jun 2026 | Demo Clinician | Referring Clinician | Recommendation | Report accessed by referring clinician | Recommendation report viewed and downloaded. |
| Pending | Demo Clinician | Referring Clinician | Follow-up | Follow-up pending | Outcome report due 15 Sep 2026. |
Operational tumor board coordination workspace for scheduled case discussion, readiness review, and recommendation workflow tracking.
Cases scheduled for upcoming multidisciplinary board discussion with readiness and board status.
| Case | Diagnosis | Priority | Readiness | Board Status |
|---|---|---|---|---|
| Athens Oncology Center | Soft Tissue Sarcoma Molecular confirmation before systemic escalation |
High | Ready | Agenda Locked |
| Thessaloniki University Hospital | GIST, uncertain subtype Pathology review and targeted therapy eligibility |
High | Needs Review | Fellow Review |
| Heraklion General Hospital | Retroperitoneal Sarcoma Surgical resectability and neoadjuvant approach |
Standard | Ready | Scheduled |
| Patras University Hospital | Osteosarcoma, recurrent Salvage therapy options and trial eligibility |
High | Ready | Scheduled |
| Larissa General Hospital | Unknown primary, sarcomatoid Comprehensive molecular profiling and diagnosis |
Standard | Missing Evidence | Evidence Pending |
| Ioannina University Hospital | Desmoid Tumor Observation versus systemic intervention decision |
Standard | Ready | Scheduled |
| Session | Board Type | Date | Cases | Status | Action |
|---|---|---|---|---|---|
| RCG-BOARD-2026-23 | Sarcoma & Rare Tumors Board | 21 May 2026 | 7 discussed | Reports Pending | |
| RCG-BOARD-2026-22 | Molecular Review Board | 14 May 2026 | 5 discussed | Complete | |
| RCG-BOARD-2026-21 | Complex Soft Tissue MDT | 7 May 2026 | 3 discussed | Complete |
Board sessions are scheduled according to referral volume, urgency, and case readiness. Recommendations are advisory and do not replace institutional clinical decision-making responsibility.
This is a multidisciplinary tumor board coordination system. Recommendations are advisory and do not replace institutional clinical decision-making responsibility.
Operational workspace for referral intake, completeness checks, access approval, board scheduling, and report dispatch.
New referrals requiring secretary or coordination team completeness review before fellow triage.
| Case | Submitted By | Institution | Tumor Type | Missing Items | Status | Action |
|---|---|---|---|---|---|---|
| Demo Clinician | Athens Oncology Center | Soft Tissue Sarcoma | Pathology addendum | Completeness Check | ||
| Dr. K. Antoniou | Thessaloniki University Hospital | GIST | None | Submitted | ||
| Dr. M. Georgiou | Patras University Hospital | Rare Neuroendocrine Tumor | Imaging link | Completeness Check |
Cases blocked from fellow triage until referrers upload evidence or clarify required fields.
| Case | Requested From | Missing Information | Requested | Status | Action |
|---|---|---|---|---|---|
| Demo Clinician | Histopathology report and molecular request confirmation | 29 May 2026 | Awaiting Referrer | ||
| Dr. P. Nikolaou | Follow-up outcome report | 24 May 2026 | Overdue |
Approval-required clinical portal access requests for institutional participation.
| Clinician Name | Specialty | Institution | Email Type | Status | Action |
|---|---|---|---|---|---|
| Dr. Sofia Marinou | Medical Oncology | Larissa General Hospital | Institutional | Pending Review | |
| Dr. Andreas Petrou | Pathology | Private Diagnostic Lab | Professional domain | Clarification Needed | |
| Dr. Eleni Stavrou | Radiation Oncology | Regional Oncology Unit | Public hospital | Pending Review |
Cases ready for agenda placement after completeness review and fellow preparation.
| Case | Priority | Fellow Status | Evidence Status | Suggested Board Session | Action |
|---|---|---|---|---|---|
| Standard | Triaged | Complete | RCG-BOARD-2026-24 | ||
| High | Bibliography ready | Complete | RCG-BOARD-2026-24 |
Issued board recommendations awaiting evidence package attachment and dispatch to the referrer.
| Case | Report Status | Bibliography Attached | Recipient | Action |
|---|---|---|---|---|
| Chair Signed | Yes | Dr. M. Georgiou | ||
| Ready for Dispatch | Yes | Dr. P. Nikolaou |
Clinical preparation workspace for triage, expert mapping, OncoAI bibliography review, and board readiness.
Cases assigned to the fellow for clinical classification, bibliography preparation, and board readiness.
| Case | Diagnosis | Priority | Clinical Question | Current Step | Action |
|---|---|---|---|---|---|
| Soft Tissue Sarcoma | High | Molecular confirmation before systemic escalation | Fellow Triage | ||
| Retroperitoneal Sarcoma | Standard | Resectability and treatment sequencing | Expert Mapping | ||
| Rare Neuroendocrine Tumor | Standard | Systemic therapy and trial orientation | Bibliography Prep |
Clinical classification workflow before expert mapping and agenda scheduling.
| Case Classification | Tumor Category | Urgency | Required Specialties | Board Suitability | Action |
|---|---|---|---|---|---|
| RCG-2026-0148 | Sarcoma | High | Medical oncology, pathology, molecular board | Suitable for next board | |
| RCG-2026-0139 | Rare solid tumor | Standard | Medical oncology, radiology | Needs evidence review |
Specialist matching for case discussion and board participation.
| Expert Name | Specialty | Tumor Subtype | Country | Availability | Pediatric/Adult | Molecular | Action | |
|---|---|---|---|---|---|---|---|---|
| Dr. Eleni Papadopoulou | Medical Oncology | Soft Tissue Sarcoma | Greece | e.papadopoulou@rareonco.gr | Available | Adult | Fusion testing | |
| Dr. Maria Conti | Pathology | Rare Neuroendocrine Tumors | Italy | m.conti@rareonco.eu | Available | Adult | IHC and sequencing | |
| Dr. Nikos Antoniou | Pediatric Oncology | Pediatric Bone Tumors | Greece | n.antoniou@rareonco.gr | Limited | Pediatric | NGS panel |
Case-specific evidence packages generated by OncoAI and reviewed by the assigned fellow.
| Case | Linked Clinical Question | OncoAI Package Status | Reviewed By Fellow | Evidence Count | Action |
|---|---|---|---|---|---|
| Should molecular confirmation precede systemic escalation? | Generated | No | 12 | ||
| Systemic sequencing and trial eligibility | Fellow Reviewed | Yes | 9 |
Case readiness status before scheduled multidisciplinary tumor board discussion.
| Case | Diagnosis | Expert Mapping | Evidence | Bibliography | Readiness |
|---|---|---|---|---|---|
| RCG-2026-0147 | Retroperitoneal Sarcoma | Complete | Complete | Attached | Ready |
| RCG-2026-0148 | Soft Tissue Sarcoma | Pending | Complete | Generated | Needs Expert Mapping |
| RCG-2026-0139 | Rare Solid Tumor | Not started | Missing pathology | Not generated | Missing Evidence |
| RCG-2026-0142 | Rare Neuroendocrine Tumor | Complete | Complete | Pending fellow review | Bibliography Pending |
Manage institutional account preferences, notifications, and secure clinical workspace access.
Notification preferences support operational coordination and referral continuity.
All referral activity within the national rare tumor network is logged for clinical governance, audit traceability, and operational security. Access to clinical information is restricted to authorized referring clinicians and board participants. Data handling complies with institutional clinical data governance policies and GDPR requirements.
Access the RareOnco Greece clinical referral workspace using approved professional credentials.
Your request has been forwarded to the RareOnco Greece coordination team for review. Approved users will receive activation instructions by email.